In this episode of Quick Medical Review, we break down Marfan Syndrome — an autosomal dominant connective tissue disorder. We cover FBN1 gene, cardiovascular complications including aortic root dilatation, lens subluxation, Ghent criteria, beta-blocker therapy, and the key differential with homocystinuria. Essential for USMLE, MRCP, PLAB, and SMLE.

Keywords: Marfan syndrome, FBN1, aortic dissection, ectopia lentis, connective tissue, genetics

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