Epigenetic modifications and cancer
Professor Skirmantas Kriaucionis aims to to elucidate the molecular function of DNA modifications in normal cells and cancer. Although all cells in ou...
Cancer
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About
Cancer is studied from several angles at NDM, from its epidemiology and potential causes, to its effect on patient lives and outcomes, as well as the basic science underpinning the unregulated cell growth that is the hallmark of the disease. Our Cancer podcasts illustrate the diversity of this research, and provide snapshots to the work of NDM scientists and clinicians to understand, treat and prevent cancer.
Repairing DNA damage
Dr Ross Chapman studies the molecular events triggered by DNA damage detection, and why defects in these events lead to immune deficiency and cancer i...
Cleaning up misfolded proteins
Misfolded proteins can either create the loss of a cellular function, or escape degradation, causing aggregation diseases. Dr John Christianson's rese...
Targeting cancer mechanisms
Professor Robert Gilbert's research focuses on the molecular mechanisms underlying membrane pore formation and cell adhesion. Switching mechanisms wit...
Melanoma
Melanoma or skin cancer is one of the fastest rising cancer types. When identified early, melanoma is relatively easy to cure, but once it starts to m...
Targeting epigenetics to treat cancer
Transcription is a tightly regulated process, where chemical modifications initiate the duplication of genetic material. This epigenetic process is of...
Human Cancer Genetics
Dr Gareth Bond, Associate Member of the Ludwig Institute for Cancer Research, studies the influence of genetic variants on the origins, progression an...
Personalised Medicine
Dr Jenny Taylor is the Programme Director for the Genomic Medicine Theme, Wellcome Trust Centre for Human Genetics. Her research bridges the gap betwe...
Cancer predisposition and evolution
Identifying genes that increase the risk of bowel or other cancers allows us to offer preventative measures, such as removing tumours at an early stag...
Cancer Informatics
Cancer research now generates huge amounts of data, and sophisticated computational tools are needed to answer biological questions. Making sense of t...