This week: a large trial finds statins cut heart attacks and strokes in healthy over seventies but do not prevent dementia or disability, a Scandinavian study of more than 280,000 people pins down who is most at risk of ketoacidosis on flozin medicines, semaglutide and tirzepatide enter the European heart failure guidelines, immune cells appear to remember obesity for years, and four medical bodies issue joint autumn vaccine advice.

statins, atorvastatin, STAREE trial, primary prevention, healthy ageing, SGLT2 inhibitors, flozins, diabetic ketoacidosis, sick day rules, type 2 diabetes, heart failure, ESC guidelines, semaglutide, tirzepatide, GLP-1, obesity, weight loss, immune system, flu vaccine, COVID vaccine, RSV