Ep 74: Antiphospholipid Syndrome

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Obgyno Wino Podcast

Miscellaneous


Practice Bulletin #132 - Published December 2012 (Reaffirmed 2017) 1. The clinical diagnosis of APS is made through a careful clinical history that takes into account thrombotic events, history of pregnancy loss, and development of preterm preeclampsia. 2. Lab studies to detect specific antibodies can confirm your diagnosis, but these lab studies are not indicated when clinical criteria are not met. 3. The three relevant antibodies on your board exam are: lupus anticoagulant, anti-β₂-glycoprotein, and anticardiolipin 4. The worst consequence of APS is thrombosis. 5. In pregnancy, thrombotic risk is EVEN higher. APS patients with history of thrombosis should be treated with prophylactic heparin throughout pregnancy until 6 weeks postpartum. Show Notes Wine pairing: 2018 Sonoma Zinfandel from Seghesio Family Vineyards Theme music by Evan Handyside Logo design by JD Dotson (jddotson1@gmail.com)