Can surgery treat arterial hypertension in patients with unilateral adrenal incidentalomas and mild autonomous cortisol secretion?

In patients with hypertension and mild autonomous cortisol secretion from a unilateral adrenal incidentaloma, adrenalectomy improved blood pressure control more than conservative management.

Randomised trial · Lancet Diabetes & Endocrinology 2025

Reference: Tabarin A, Espiard S, Deutschbein T, et al. CHIRACIC: adrenalectomy versus conservative management in patients with unilateral adrenal incidentaloma and mild autonomous cortisol secretion. Lancet Diabetes Endocrinol. 2025. DOI:10.1016/S2213-8587(25)00062-2. PMID:40373786. https://pubmed.ncbi.nlm.nih.gov/40373786/

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