Science
CME credits: 0.50 Valid until: 09-07-2022 Claim your CME credit at https://reachmd.com/programs/cme/changing-treatment-paradigms-in-type-1-diabetes-role-of-anti-cd3-targeted-therapy-screening-for-islet-autoantibodies-in-children-and-adolescents-to-preventdelay-t1d/12695/ Experts in the immunopathology of type 1 diabetes review data showing that clinical presentation is preceded by an asymptomatic phase, characterized by the presence of one or more islet autoantibodies. Screening children for islet autoantibodies during the two preclinical stages can identify those with multiple autoantibodies and high-risk antibody phenotypes who may be candidates for preventive interventions before developing dysglycemia or the clinical onset of type 1 diabetes.